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Compatibility of pedigree-based and marker-based relationship matrices for single-step genetic evaluation

Overview of attention for article published in Genetics Selection Evolution, December 2012
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Title
Compatibility of pedigree-based and marker-based relationship matrices for single-step genetic evaluation
Published in
Genetics Selection Evolution, December 2012
DOI 10.1186/1297-9686-44-37
Pubmed ID
Authors

Ole F Christensen

Abstract

Single-step methods provide a coherent and conceptually simple approach to incorporate genomic information into genetic evaluations. An issue with single-step methods is compatibility between the marker-based relationship matrix for genotyped animals and the pedigree-based relationship matrix. Therefore, it is necessary to adjust the marker-based relationship matrix to the pedigree-based relationship matrix. Moreover, with data from routine evaluations, this adjustment should in principle be based on both observed marker genotypes and observed phenotypes, but until now this has been overlooked. In this paper, I propose a new method to address this issue by 1) adjusting the pedigree-based relationship matrix to be compatible with the marker-based relationship matrix instead of the reverse and 2) extending the single-step genetic evaluation using a joint likelihood of observed phenotypes and observed marker genotypes. The performance of this method is then evaluated using two simulated datasets.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
France 1 1%
Argentina 1 1%
Brazil 1 1%
Unknown 77 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 25%
Student > Ph. D. Student 19 23%
Student > Master 10 12%
Student > Doctoral Student 4 5%
Other 3 4%
Other 9 11%
Unknown 16 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 53 65%
Biochemistry, Genetics and Molecular Biology 3 4%
Medicine and Dentistry 2 2%
Mathematics 2 2%
Veterinary Science and Veterinary Medicine 1 1%
Other 2 2%
Unknown 18 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2015.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Genetics Selection Evolution
#550
of 822 outputs
Outputs of similar age
#191,702
of 286,152 outputs
Outputs of similar age from Genetics Selection Evolution
#5
of 7 outputs
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So far Altmetric has tracked 822 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
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