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Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

Overview of attention for article published in BMC Musculoskeletal Disorders, December 2012
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1 Facebook page

Citations

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22 Mendeley
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Title
Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats
Published in
BMC Musculoskeletal Disorders, December 2012
DOI 10.1186/1471-2474-13-240
Pubmed ID
Authors

Ola Belfrage, Hanna Isaksson, Magnus Tägil

Abstract

Bone grafts are frequently used in orthopaedic surgery. Graft remodelling is advantageous but can occur too quickly, and premature bone resorption might lead to decreased mechanical integrity of the graft. Bisphosphonates delay osteoclastic bone resorption but may also impair formation of new bone. We hypothesize that these effects are dose dependent. In the present study we evaluate different ways of applying bisphosphonates locally to the graft in a bone chamber model, and compare that with systemic treatment.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 6 27%
Student > Ph. D. Student 5 23%
Researcher 5 23%
Lecturer > Senior Lecturer 2 9%
Student > Bachelor 1 5%
Other 0 0%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 6 27%
Materials Science 4 18%
Biochemistry, Genetics and Molecular Biology 3 14%
Computer Science 1 5%
Agricultural and Biological Sciences 1 5%
Other 1 5%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2012.
All research outputs
#20,176,348
of 22,689,790 outputs
Outputs from BMC Musculoskeletal Disorders
#3,611
of 4,028 outputs
Outputs of similar age
#246,306
of 277,751 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#78
of 96 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,028 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,751 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.