Title |
Open-label trial of three dosage regimens of fixed-dose combination of artemisinin and naphthoquine for treating uncomplicated falciparum malaria in calabar, Nigeria
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Published in |
Malaria Journal, December 2012
|
DOI | 10.1186/1475-2875-11-413 |
Pubmed ID | |
Authors |
Martin M Meremikwu, Friday Odey, Chioma Oringanje, Angela Oyo-ita, Emmanuel Effa, Ekpereonne B Esu, Eyam Eyam, Olabisi Oduwole, Vivian Asiegbu, Ambrose Alaribe, Emmanuel N Ezedinachi |
Abstract |
The use of anti-malarial drug combinations with artemisinin, or with one of its derivatives, is now widely recommended to overcome drug resistance in falciparum malaria. Fixed-dose combination of artemisinin and naphthoquine is a new generation artemisinin combination therapy (ACT) offered as a single dose therapy. The aim of the study was to assess the therapeutic efficacy, safety and tolerability of three dosage schedules of fixed-dose combination of artemisinin (125 mg) and naphthoquine (50 mg) for treating uncomplicated Plasmodium falciparum malaria among adolescents and adults in Calabar, South-east Nigeria. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 3% |
Belgium | 1 | 2% |
Unknown | 58 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 18% |
Student > Ph. D. Student | 10 | 16% |
Researcher | 7 | 11% |
Student > Bachelor | 5 | 8% |
Other | 5 | 8% |
Other | 17 | 28% |
Unknown | 6 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 39% |
Biochemistry, Genetics and Molecular Biology | 5 | 8% |
Agricultural and Biological Sciences | 5 | 8% |
Nursing and Health Professions | 3 | 5% |
Psychology | 3 | 5% |
Other | 13 | 21% |
Unknown | 8 | 13% |