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Open-label trial of three dosage regimens of fixed-dose combination of artemisinin and naphthoquine for treating uncomplicated falciparum malaria in calabar, Nigeria

Overview of attention for article published in Malaria Journal, December 2012
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Title
Open-label trial of three dosage regimens of fixed-dose combination of artemisinin and naphthoquine for treating uncomplicated falciparum malaria in calabar, Nigeria
Published in
Malaria Journal, December 2012
DOI 10.1186/1475-2875-11-413
Pubmed ID
Authors

Martin M Meremikwu, Friday Odey, Chioma Oringanje, Angela Oyo-ita, Emmanuel Effa, Ekpereonne B Esu, Eyam Eyam, Olabisi Oduwole, Vivian Asiegbu, Ambrose Alaribe, Emmanuel N Ezedinachi

Abstract

The use of anti-malarial drug combinations with artemisinin, or with one of its derivatives, is now widely recommended to overcome drug resistance in falciparum malaria. Fixed-dose combination of artemisinin and naphthoquine is a new generation artemisinin combination therapy (ACT) offered as a single dose therapy. The aim of the study was to assess the therapeutic efficacy, safety and tolerability of three dosage schedules of fixed-dose combination of artemisinin (125 mg) and naphthoquine (50 mg) for treating uncomplicated Plasmodium falciparum malaria among adolescents and adults in Calabar, South-east Nigeria.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 3%
Belgium 1 2%
Unknown 58 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 18%
Student > Ph. D. Student 10 16%
Researcher 7 11%
Student > Bachelor 5 8%
Other 5 8%
Other 17 28%
Unknown 6 10%
Readers by discipline Count As %
Medicine and Dentistry 24 39%
Biochemistry, Genetics and Molecular Biology 5 8%
Agricultural and Biological Sciences 5 8%
Nursing and Health Professions 3 5%
Psychology 3 5%
Other 13 21%
Unknown 8 13%