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Onset of polyarticular juvenile idiopathic arthritis with both anti-cyclic citrullinated peptide antibodies and rheumatoid factor in a 3-year-old girl

Overview of attention for article published in Pediatric Rheumatology, December 2012
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Title
Onset of polyarticular juvenile idiopathic arthritis with both anti-cyclic citrullinated peptide antibodies and rheumatoid factor in a 3-year-old girl
Published in
Pediatric Rheumatology, December 2012
DOI 10.1186/1546-0096-10-41
Pubmed ID
Authors

Kozo Yasui, Sonoko Sakata, Hideaki Ochi, Shinji Itamura, Kenta Hirai, Mieko Takenaka, Osamu Mitani, Kazunori Ogawa, Kuniaki Iyoda

Abstract

This report describes 3 year old girl with the unusual presentation of polyarticular juvenile idiopathic arthritis (JIA) with anti-cyclic citrullinated peptide (anti-CCP) antibodies and a positive rheumatoid factor (RF). She was initially treated with a nonsteroidal anti-inflammatory drug (NSAID; ibuprofen) followed by methotrexate (MTX, 10 mg/m2/week) and prednisolone (0.25 mg/kg/day), but these treatments were ineffective. Administration of tocilizumab, a humanized antihuman interleukin-6 receptor monoclonal antibody, promptly improved her clinical manifestations, and she has been in complete remission (DAS28 <2.6) without bone erosion and/or destruction. Positivity for both antibodies (anti-CCP and RF) can forecast the severity of JIA (radiographic bone destruction). In such cases the administration of biologic remissive therapy may be prudent early in the disease course.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 20%
Researcher 3 15%
Other 2 10%
Student > Master 2 10%
Student > Ph. D. Student 2 10%
Other 3 15%
Unknown 4 20%
Readers by discipline Count As %
Medicine and Dentistry 9 45%
Unspecified 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Arts and Humanities 1 5%
Agricultural and Biological Sciences 1 5%
Other 3 15%
Unknown 4 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2012.
All research outputs
#15,258,711
of 22,689,790 outputs
Outputs from Pediatric Rheumatology
#453
of 691 outputs
Outputs of similar age
#180,031
of 278,829 outputs
Outputs of similar age from Pediatric Rheumatology
#3
of 7 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 691 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,829 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.