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Signs of dysregulated fibrinolysis precede the development of type 2 diabetes mellitus in a population-based study

Overview of attention for article published in Cardiovascular Diabetology, December 2012
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Title
Signs of dysregulated fibrinolysis precede the development of type 2 diabetes mellitus in a population-based study
Published in
Cardiovascular Diabetology, December 2012
DOI 10.1186/1475-2840-11-152
Pubmed ID
Authors

Jenny Hernestål-Boman, Margareta Norberg, Jan-Hakan Jansson, Mats Eliasson, Jan W Eriksson, Bernt Lindahl, Lars Johansson

Abstract

Diabetic patients experience stimulated coagulation and dysfibrinolysis, which is associated with an increased risk of cardiovascular events. This imbalance may precede the manifest diagnosis. We investigated whether elevated antigen levels of tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1), the tPA/PAI-1 complex, or von Willebrand Factor (VWF) precede type 2 diabetes mellitus (T2DM) diagnosis, and whether this elevation occurs before increased fasting plasma glucose (FPG) or 2-hour plasma glucose (2hPG) in individuals who later develop T2DM.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 42 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 16%
Student > Master 7 16%
Student > Ph. D. Student 5 12%
Student > Bachelor 4 9%
Student > Doctoral Student 2 5%
Other 8 19%
Unknown 10 23%
Readers by discipline Count As %
Medicine and Dentistry 12 28%
Nursing and Health Professions 4 9%
Agricultural and Biological Sciences 3 7%
Biochemistry, Genetics and Molecular Biology 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 8 19%
Unknown 12 28%