Title |
Ocular symptoms secondary to meningeal carcinomatosis in a patient with lung adenocarcinoma: a case report
|
---|---|
Published in |
BMC Ophthalmology, December 2012
|
DOI | 10.1186/1471-2415-12-65 |
Pubmed ID | |
Authors |
Alfonso L Sabater, Luis M Sadaba, Elisa de Nova |
Abstract |
Meningeal carcinomatosis (MC) is a rare complication associated with hematologic and solid tumors. MC develops when malignant cells gain access to the leptomeningeal space, producing several clinical symptoms. Loss of vision and ocular motility deficit are the most frequent ocular symptoms reported. Fundus examination usually appears normal, although optic nerve alterations like optic atrophy or papilledema have been described. MC diagnosis is usually completed by magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) analysis. Indicated treatment for MC usually involves intrathecal chemotherapy combined with radiotherapy, although survival rate is extremely low. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 4 | 16% |
Student > Ph. D. Student | 3 | 12% |
Researcher | 3 | 12% |
Student > Master | 3 | 12% |
Student > Bachelor | 2 | 8% |
Other | 3 | 12% |
Unknown | 7 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 52% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Social Sciences | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Unknown | 8 | 32% |