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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Does sumatriptan cross the blood–brain barrier in animals and man?
|
|---|---|
| Published in |
The Journal of Headache and Pain, December 2009
|
| DOI | 10.1007/s10194-009-0170-y |
| Pubmed ID | |
| Authors |
Peer Carsten Tfelt-Hansen |
| Abstract |
Sumatriptan, a relatively hydrophilic triptan, based on several animal studies has been regarded to be unable to cross the blood-brain barrier (BBB). In more recent animal studies there are strong indications that sumatriptan to some extent can cross the BBB. The CNS adverse events of sumatriptan in migraine patients and normal volunteers also indicate a more general effect of sumatriptan on CNS indicating that the drug can cross the BBB in man. It has been discussed whether a defect in the BBB during migraine attacks could be responsible for a possible central effect of sumatriptan in migraine. This review suggests that there is no need for a breakdown in the BBB to occur in order to explain a possible central CNS effect of sumatriptan. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 1% |
| Unknown | 67 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 15% |
| Researcher | 10 | 15% |
| Student > Bachelor | 10 | 15% |
| Other | 8 | 12% |
| Student > Master | 7 | 10% |
| Other | 12 | 18% |
| Unknown | 11 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 22% |
| Agricultural and Biological Sciences | 13 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 9% |
| Neuroscience | 4 | 6% |
| Nursing and Health Professions | 3 | 4% |
| Other | 9 | 13% |
| Unknown | 18 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2022.
All research outputs
#7,335,210
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#670
of 1,417 outputs
Outputs of similar age
#47,117
of 169,980 outputs
Outputs of similar age from The Journal of Headache and Pain
#2
of 6 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.6. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,980 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.