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CMPF: Class-switching minimized pathfinding in metabolic networks

Overview of attention for article published in BMC Bioinformatics, December 2012
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Title
CMPF: Class-switching minimized pathfinding in metabolic networks
Published in
BMC Bioinformatics, December 2012
DOI 10.1186/1471-2105-13-s17-s17
Pubmed ID
Authors

Kevin Lim, Limsoon Wong

Abstract

The metabolic network is an aggregation of enzyme catalyzed reactions that converts one compound to another. Paths in a metabolic network are a sequence of enzymes that describe how a chemical compound of interest can be produced in a biological system. As the number of such paths is quite large, many methods have been developed to score paths so that the k-shortest paths represent the set of paths that are biologically meaningful or efficient. However, these approaches do not consider whether the sequence of enzymes can be manufactured in the same pathway/species/localization. As a result, a predicted sequence might consist of groups of enzymes that operate in distinct pathway/species/localization and may not truly reflect the events occurring within cell.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 53%
Student > Master 5 26%
Student > Bachelor 1 5%
Other 1 5%
Professor > Associate Professor 1 5%
Other 0 0%
Unknown 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 26%
Computer Science 5 26%
Biochemistry, Genetics and Molecular Biology 2 11%
Engineering 2 11%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 1 5%
Unknown 3 16%