Title |
The significance of 18F-FDG PET/CT in secondary hemophagocytic lymphohistiocytosis
|
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Published in |
Journal of Hematology & Oncology, July 2012
|
DOI | 10.1186/1756-8722-5-40 |
Pubmed ID | |
Authors |
Li-Juan Zhang, Ji Xu, Peng Liu, Chong-Yang Ding, Jian-Yong Li, Hong-Xia Qiu, Su-Jiang Zhang |
Abstract |
This study was aimed to investigate the significance of 18F-FDG PET/CT in secondary hemophagocytic lymphohistiocytosis (sHLH) patients. A total of 18 patients received 18F-FDG PET/CT scan at initial diagnosis. All patients (18/18) had at least 3 organs involved, with increased FDG metabolism in different degrees. Fifteen cases (15/18) had definite underlying diseases, including infections (IAHLH), rheumatosis (RAHLH), or malignancy (MAHLH). The SUVmax of patients in MAHLH group was significantly higher than patients in IAHLH group or RAHLH group (P = 0.015, P = 0.045). Furthermore, the SUVmax of patients in IAHLH group was significantly higher than patients of RAHLH group (P = 0.043). Therefore, we concluded that 18F-FDG PET/CT may especially play important role in differential diagnosis of sHLH. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Postgraduate | 2 | 22% |
Student > Master | 2 | 22% |
Lecturer > Senior Lecturer | 1 | 11% |
Other | 1 | 11% |
Researcher | 1 | 11% |
Other | 0 | 0% |
Unknown | 2 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 56% |
Immunology and Microbiology | 1 | 11% |
Unknown | 3 | 33% |