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Does IFN-γ play a role on the pathogenesis of non-atopic asthma in Latin America children?

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, December 2012
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Title
Does IFN-γ play a role on the pathogenesis of non-atopic asthma in Latin America children?
Published in
Allergy, Asthma & Clinical Immunology, December 2012
DOI 10.1186/1710-1492-8-18
Pubmed ID
Authors

Camila Alexandrina Figueiredo, Laura Cunha Rodrigues, Neuza Maria Alcantara-Neves, Philip J Cooper, Leila Denise Amorim, Nivea Bispo Silva, Alvaro A Cruz, Mauricio Lima Barreto

Abstract

In this work we explore differences in blood cells and cytokine profiles in children according to atopic status and asthma (atopic or non-atopic). The study involved measurement of Th1(IFN-γ) and Th2 (IL-5 and IL-13) cytokines in Dermatophagoides pteronyssinus stimulated peripheral blood leukocytes, blood cell count, skin prick test and specific IgE against common aeroallergens. Atopic status was associated with eosinophilia and production of Th2 type cytokines. Atopic asthma was associated with eosinophilia and non-atopic asthma was associated with IFN-γ and elevated monocytes in blood. IFN-γ and monocytes might play a role in immunopathology of non-atopic asthma in Latin American children.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 20%
Student > Master 5 17%
Other 3 10%
Professor 2 7%
Student > Doctoral Student 2 7%
Other 7 23%
Unknown 5 17%
Readers by discipline Count As %
Immunology and Microbiology 7 23%
Medicine and Dentistry 4 13%
Agricultural and Biological Sciences 4 13%
Environmental Science 3 10%
Biochemistry, Genetics and Molecular Biology 2 7%
Other 5 17%
Unknown 5 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2012.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#884
of 924 outputs
Outputs of similar age
#258,208
of 288,496 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#4
of 4 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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