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Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety

Overview of attention for article published in BMC Pharmacology and Toxicology, October 2012
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2 X users

Citations

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13 Dimensions

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19 Mendeley
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Title
Decreased cervical epithelial sensitivity to nonoxynol-9 (N-9) after four daily applications in a murine model of topical vaginal microbicide safety
Published in
BMC Pharmacology and Toxicology, October 2012
DOI 10.1186/2050-6511-13-9
Pubmed ID
Authors

Karissa Lozenski, Robert Ownbey, Brian Wigdahl, Tina Kish-Catalone, Fred C Krebs

Abstract

The disappointing clinical failures of five topical vaginal microbicides have provided new insights into factors that impact microbicide safety and efficacy. Specifically, the greater risk for human immunodeficiency virus type 1 (HIV-1) acquisition associated with multiple uses of a nonoxynol-9 (N-9)-containing product has highlighted the importance of application frequency as a variable during pre-clinical microbicide development, particularly in animal model studies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 37%
Student > Ph. D. Student 2 11%
Other 2 11%
Professor > Associate Professor 2 11%
Researcher 1 5%
Other 0 0%
Unknown 5 26%
Readers by discipline Count As %
Medicine and Dentistry 3 16%
Agricultural and Biological Sciences 3 16%
Environmental Science 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Chemical Engineering 1 5%
Other 3 16%
Unknown 7 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2013.
All research outputs
#14,613,720
of 22,689,790 outputs
Outputs from BMC Pharmacology and Toxicology
#219
of 438 outputs
Outputs of similar age
#103,088
of 172,115 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#7
of 12 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 438 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,115 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.