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Cytokine profile, proliferation and phosphorylation of ERK1/2 and Akt in circulating mononuclear cells from individuals during the chronic intestinal phase of Schistosomiasis mansoni infection

Overview of attention for article published in BMC Infectious Diseases, December 2012
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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2 tweeters

Citations

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3 Dimensions

Readers on

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24 Mendeley
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Title
Cytokine profile, proliferation and phosphorylation of ERK1/2 and Akt in circulating mononuclear cells from individuals during the chronic intestinal phase of Schistosomiasis mansoni infection
Published in
BMC Infectious Diseases, December 2012
DOI 10.1186/1471-2334-12-380
Pubmed ID
Authors

Roberta Oliveira-Prado, Iramaya Rodrigues Caldas, Andréa Teixeira-Carvalho, Marcus Vinicius Andrade, Rafaelle Christine Gomes Fares, Laís Maroni Portugal, Andréa Gazzinelli, Rodrigo Corrêa-Oliveira, José Renan Cunha-Melo

Abstract

The immune response to Schistosoma mansoni is characterized by a granulomatous reaction around the parasite eggs that are trapped in the host liver, and this reaction modulates the immune response during the chronic phase of the disease. The typical peripheral blood mononuclear cell (PBMC) response of patients during the chronic intestinal phase of infection is characterized by a decreased response to an S. mansoni soluble egg antigen. To obtain a greater understanding of Schistosoma infections, this study investigated the effects of the soluble egg antigen (SEA) and soluble adult worm antigen (SWAP) of S. mansoni on cellular proliferation, cytokine production, and ERK1/2 and Akt phosphorylation in PBMCs from infected (XTO) and egg-negative (NI) individuals living in the same endemic area.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 17%
Student > Doctoral Student 3 13%
Student > Master 3 13%
Professor > Associate Professor 3 13%
Student > Bachelor 3 13%
Other 5 21%
Unknown 3 13%
Readers by discipline Count As %
Medicine and Dentistry 7 29%
Agricultural and Biological Sciences 5 21%
Immunology and Microbiology 2 8%
Veterinary Science and Veterinary Medicine 1 4%
Nursing and Health Professions 1 4%
Other 5 21%
Unknown 3 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2012.
All research outputs
#2,304,351
of 5,028,115 outputs
Outputs from BMC Infectious Diseases
#1,184
of 2,669 outputs
Outputs of similar age
#115,727
of 286,957 outputs
Outputs of similar age from BMC Infectious Diseases
#92
of 213 outputs
Altmetric has tracked 5,028,115 research outputs across all sources so far. This one has received more attention than most of these and is in the 51st percentile.
So far Altmetric has tracked 2,669 research outputs from this source. They receive a mean Attention Score of 3.2. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,957 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 213 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.