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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system
|
|---|---|
| Published in |
Journal of Inflammation, May 2011
|
| DOI | 10.1186/1476-9255-8-11 |
| Pubmed ID | |
| Authors |
Anna Vossenkämper, Thomas T MacDonald, Olivier Marchès |
| Abstract |
The intestinal immune system and the epithelium are the first line of defense in the gut. Constantly exposed to microorganisms from the environment, the gut has complex defense mechanisms to prevent infections, as well as regulatory pathways to tolerate commensal bacteria and food antigens. Intestinal pathogens have developed strategies to regulate intestinal immunity and inflammation in order to establish or prolong infection. The organisms that employ a type III secretion system use a molecular syringe to deliver effector proteins into the cytoplasm of host cells. These effectors target the host cell cytoskeleton, cell organelles and signaling pathways. This review addresses the multiple mechanisms by which the type III secretion system targets the intestinal immune response, with a special focus on pathogenic E. coli. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 75% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| Germany | 1 | 1% |
| Unknown | 64 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 30% |
| Student > Ph. D. Student | 12 | 18% |
| Student > Bachelor | 8 | 12% |
| Student > Master | 6 | 9% |
| Student > Postgraduate | 5 | 7% |
| Other | 11 | 16% |
| Unknown | 5 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 40 | 60% |
| Biochemistry, Genetics and Molecular Biology | 9 | 13% |
| Immunology and Microbiology | 8 | 12% |
| Chemistry | 2 | 3% |
| Neuroscience | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 6 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2022.
All research outputs
#6,754,661
of 25,374,917 outputs
Outputs from Journal of Inflammation
#74
of 425 outputs
Outputs of similar age
#37,181
of 122,074 outputs
Outputs of similar age from Journal of Inflammation
#2
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 425 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 122,074 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.