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Revisiting the pathogenesis of podagra: why does gout target the foot?

Overview of attention for article published in Journal of Foot and Ankle Research, May 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
5 tweeters
googleplus
2 Google+ users
q&a
1 Q&A thread

Citations

dimensions_citation
60 Dimensions

Readers on

mendeley
84 Mendeley
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Title
Revisiting the pathogenesis of podagra: why does gout target the foot?
Published in
Journal of Foot and Ankle Research, May 2011
DOI 10.1186/1757-1146-4-13
Pubmed ID
Authors

Edward Roddy

Abstract

This invited paper provides a summary of a keynote lecture delivered at the 2011 Australasian Podiatry Conference. Gout is the most prevalent inflammatory arthropathy. It displays a striking predilection to affect the first metatarsophalangeal joint as well as joints within the mid-foot and ankle. A number of factors are known to reduce urate solubility and enhance nucleation of monosodium urate crystals including decreased temperature, lower pH and physical shock, all of which may be particularly relevant to crystal deposition in the foot. An association has also been proposed between monosodium urate crystal deposition and osteoarthritis, which also targets the first metatarsophalangeal joint. Cadaveric, clinical and radiographic studies indicate that monosodium urate crystals more readily deposit in osteoarthritic cartilage. Transient intra-articular hyperuricaemia and precipitation of monosodium urate crystals is thought to follow overnight resolution of synovial effusion within the osteoarthritic first metatarsophalangeal joint. The proclivity of gout for the first metatarsophalangeal joint is likely to be multi-factorial in origin, arising from the unique combination of the susceptibility of the joint to osteoarthritis and other determinants of urate solubility and crystal nucleation such as temperature and minor physical trauma which are particularly relevant to the foot.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Unknown 83 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 21 25%
Student > Master 14 17%
Researcher 8 10%
Student > Postgraduate 7 8%
Student > Ph. D. Student 7 8%
Other 16 19%
Unknown 11 13%
Readers by discipline Count As %
Medicine and Dentistry 36 43%
Nursing and Health Professions 14 17%
Biochemistry, Genetics and Molecular Biology 6 7%
Agricultural and Biological Sciences 5 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 6 7%
Unknown 15 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2021.
All research outputs
#1,275,941
of 21,342,999 outputs
Outputs from Journal of Foot and Ankle Research
#80
of 737 outputs
Outputs of similar age
#14,299
of 292,699 outputs
Outputs of similar age from Journal of Foot and Ankle Research
#2
of 42 outputs
Altmetric has tracked 21,342,999 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 737 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,699 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.