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Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model

Overview of attention for article published in BMC Neuroscience, January 2013
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Title
Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model
Published in
BMC Neuroscience, January 2013
DOI 10.1186/1471-2202-14-6
Pubmed ID
Authors

David Amschl, Jörg Neddens, Daniel Havas, Stefanie Flunkert, Roland Rabl, Heinrich Römer, Edward Rockenstein, Eliezer Masliah, Manfred Windisch, Birgit Hutter-Paier

Abstract

Progressive accumulation of α-synuclein (α-Syn) protein in different brain regions is a hallmark of synucleinopathic diseases, such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. α-Syn transgenic mouse models have been developed to investigate the effects of α-Syn accumulation on behavioral deficits and neuropathology. However, the onset and progression of pathology in α-Syn transgenic mice have not been fully characterized. For this purpose we investigated the time course of behavioral deficits and neuropathology in PDGF-β human wild type α-Syn transgenic mice (D-Line) between 3 and 12 months of age.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Sweden 1 1%
Unknown 81 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 23%
Researcher 17 20%
Student > Bachelor 11 13%
Student > Master 11 13%
Professor 3 4%
Other 8 10%
Unknown 14 17%
Readers by discipline Count As %
Neuroscience 20 24%
Agricultural and Biological Sciences 19 23%
Biochemistry, Genetics and Molecular Biology 11 13%
Medicine and Dentistry 8 10%
Psychology 3 4%
Other 5 6%
Unknown 17 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2013.
All research outputs
#20,178,031
of 22,691,736 outputs
Outputs from BMC Neuroscience
#1,051
of 1,240 outputs
Outputs of similar age
#250,027
of 282,271 outputs
Outputs of similar age from BMC Neuroscience
#18
of 31 outputs
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