Title |
Tobacco use increases susceptibility to bacterial infection
|
---|---|
Published in |
Tobacco Induced Diseases, December 2008
|
DOI | 10.1186/1617-9625-4-12 |
Pubmed ID | |
Authors |
Juhi Bagaitkar, Donald R Demuth, David A Scott |
Abstract |
Active smokers and those exposed to secondhand smoke are at increased risk of bacterial infection. Tobacco smoke exposure increases susceptibility to respiratory tract infections, including tuberculosis, pneumonia and Legionnaires disease; bacterial vaginosis and sexually transmitted diseases, such as chlamydia and gonorrhoea; Helicobacter pylori infection; periodontitis; meningitis; otitis media; and post-surgical and nosocomial infections. Tobacco smoke compromises the anti-bacterial function of leukocytes, including neutrophils, monocytes, T cells and B cells, providing a mechanistic explanation for increased infection risk. Further epidemiological, clinical and mechanistic research into this important area is warranted. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 29% |
Canada | 2 | 29% |
United Kingdom | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | <1% |
India | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 198 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 36 | 18% |
Student > Master | 29 | 14% |
Researcher | 19 | 9% |
Student > Ph. D. Student | 17 | 8% |
Student > Doctoral Student | 15 | 7% |
Other | 41 | 20% |
Unknown | 44 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 69 | 34% |
Agricultural and Biological Sciences | 21 | 10% |
Biochemistry, Genetics and Molecular Biology | 13 | 6% |
Immunology and Microbiology | 13 | 6% |
Nursing and Health Professions | 12 | 6% |
Other | 20 | 10% |
Unknown | 53 | 26% |