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Intermittent preventive treatment for malaria in pregnancy in Africa: What's new, what's needed?

Overview of attention for article published in Malaria Journal, February 2007
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Title
Intermittent preventive treatment for malaria in pregnancy in Africa: What's new, what's needed?
Published in
Malaria Journal, February 2007
DOI 10.1186/1475-2875-6-16
Pubmed ID
Authors

Andrew Vallely, Lisa Vallely, John Changalucha, Brian Greenwood, Daniel Chandramohan

Abstract

Falciparum malaria is an important cause of maternal, perinatal and neonatal morbidity in high transmission settings in Sub-Saharan Africa. Intermittent preventive treatment with sulphadoxine-pyrimethamine (SP-IPT) has proven efficacious in reducing the burden of pregnancy-associated malaria but increasing levels of parasite resistance mean that the benefits of national SP-IPT programmes may soon be seriously undermined in much of the region. Hence, there is an urgent need to develop alternative drug regimens for IPT in pregnancy. This paper reviews published safety and efficacy data on various antimalarials and proposes several candidate combination regimens for assessment in phase II/III clinical trials.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 2%
Tanzania, United Republic of 2 1%
Brazil 1 <1%
Burkina Faso 1 <1%
Thailand 1 <1%
United States 1 <1%
Unknown 149 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 29 18%
Student > Ph. D. Student 25 16%
Researcher 21 13%
Other 12 8%
Student > Bachelor 11 7%
Other 33 21%
Unknown 27 17%
Readers by discipline Count As %
Medicine and Dentistry 54 34%
Agricultural and Biological Sciences 22 14%
Nursing and Health Professions 14 9%
Social Sciences 8 5%
Biochemistry, Genetics and Molecular Biology 7 4%
Other 23 15%
Unknown 30 19%