↓ Skip to main content

Crosstalk between purinergic receptors and lipid mediators in leishmaniasis

Overview of attention for article published in Parasites & Vectors, September 2016
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
20 Dimensions

Readers on

mendeley
57 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Crosstalk between purinergic receptors and lipid mediators in leishmaniasis
Published in
Parasites & Vectors, September 2016
DOI 10.1186/s13071-016-1781-1
Pubmed ID
Authors

Mariana M. Chaves, Cláudio Canetti, Robson Coutinho-Silva

Abstract

Leishmaniasis is a neglected tropical disease affecting millions of people around the world caused by organisms of the genus Leishmania. Parasite escape mechanisms of the immune system confer the possibility of resistance and dissemination of the disease. A group of molecules that has become a target for Leishmania survival strategies are lipid mediators. Among them, leukotriene B4 (LTB4) has been described as a pro-inflammatory molecule capable of activating cells of the immune system to combat Leishmania. In an opposite way, prostaglandin E2 (PGE2) is a lipid mediator described as a deactivator of macrophages and neutrophils. The balance of these two molecules can be generated by extracellular nucleotides, such as adenosine 5'-triphosphate (ATP) and adenosine (Ado), which activate the purinergic receptors system. Herein, we discuss the role of extracellular nucleotides and the resulting balance of LTB4 and PGE2 in Leishmania fate, survival or death.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 18%
Student > Doctoral Student 8 14%
Student > Bachelor 8 14%
Student > Ph. D. Student 6 11%
Researcher 5 9%
Other 9 16%
Unknown 11 19%
Readers by discipline Count As %
Immunology and Microbiology 11 19%
Biochemistry, Genetics and Molecular Biology 10 18%
Agricultural and Biological Sciences 7 12%
Medicine and Dentistry 5 9%
Nursing and Health Professions 2 4%
Other 8 14%
Unknown 14 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2016.
All research outputs
#18,469,995
of 22,886,568 outputs
Outputs from Parasites & Vectors
#4,237
of 5,475 outputs
Outputs of similar age
#256,728
of 335,704 outputs
Outputs of similar age from Parasites & Vectors
#104
of 128 outputs
Altmetric has tracked 22,886,568 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,475 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,704 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 128 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.