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Electrophysiological and pharmacological evaluation of the nicotinic cholinergic system in chagasic rats

Overview of attention for article published in BMC Pharmacology and Toxicology, January 2013
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Title
Electrophysiological and pharmacological evaluation of the nicotinic cholinergic system in chagasic rats
Published in
BMC Pharmacology and Toxicology, January 2013
DOI 10.1186/2050-6511-14-2
Pubmed ID
Authors

Rafael Bonfante-Cabarcas, Erlymar López Hincapié, Eliezer Jiménez Hernández, Ruth Fonseca Zambrano, Lady Ferrer Mancini, Marcos Durand Mena, Claudina Rodríguez-Bonfante

Abstract

Two theories attempt to explain the changes observed in the nicotinic acetylcholine receptors (nAChRs) in chagasic cardiomyopathy. The neurogenic theory proposes that receptor changes are due to loss of intracardiac ganglia parasympathetic neurons. The immunogenic theory proposes that the nAChRs changes are the result of autoantibodies against these receptors. Both theories agreed that nAChRs functional expression could be impaired in Chagas disease.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 24%
Student > Bachelor 3 18%
Professor > Associate Professor 2 12%
Professor 1 6%
Student > Doctoral Student 1 6%
Other 1 6%
Unknown 5 29%
Readers by discipline Count As %
Medicine and Dentistry 6 35%
Agricultural and Biological Sciences 4 24%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Engineering 1 6%
Unknown 5 29%