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Use of "biokitHSV-2 Rapid Assay" to improve the positive predictive value of Focus HerpeSelect HSV-2 ELISA

Overview of attention for article published in BMC Infectious Diseases, October 2005
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
3 news outlets
policy
1 policy source
reddit
1 Redditor

Citations

dimensions_citation
67 Dimensions

Readers on

mendeley
24 Mendeley
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Title
Use of "biokitHSV-2 Rapid Assay" to improve the positive predictive value of Focus HerpeSelect HSV-2 ELISA
Published in
BMC Infectious Diseases, October 2005
DOI 10.1186/1471-2334-5-84
Pubmed ID
Authors

Rhoda Ashley Morrow, David Friedrich, Amalia Meier, Lawrence Corey

Abstract

Commercially available assays to detect antibodies to the herpes simplex virus type 2 (HSV-2)-specific glycoprotein gG-2 have markedly improved serologic diagnosis of HSV-2 infection. However, even tests with high specificity can have low positive predictive values in low prevalence populations. HSV-2 is a chronic, life-long viral infection that requires both medical attention and potential alterations in health care strategy. As such, the concern for false positive diagnoses is high confirmatory testing is routine for other viral serologies such as HIV and hepatitis C. We evaluated such a strategy for HSV-2 serology by using an easily performed commercial test, biokitHSV-2 rapid test ("Biokit"; Biokit USA, Lexington MA) as a confirmatory test for the widely used gG-2 specific serology ("Focus;" HerpeSelect HSV-2 ELISA; Focus Diagnostics, Cypress CA).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Other 4 17%
Student > Master 3 13%
Student > Ph. D. Student 2 8%
Student > Doctoral Student 2 8%
Other 3 13%
Unknown 5 21%
Readers by discipline Count As %
Medicine and Dentistry 10 42%
Nursing and Health Professions 3 13%
Agricultural and Biological Sciences 2 8%
Arts and Humanities 1 4%
Environmental Science 1 4%
Other 3 13%
Unknown 4 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2023.
All research outputs
#1,231,695
of 24,736,359 outputs
Outputs from BMC Infectious Diseases
#286
of 8,300 outputs
Outputs of similar age
#1,642
of 65,163 outputs
Outputs of similar age from BMC Infectious Diseases
#1
of 11 outputs
Altmetric has tracked 24,736,359 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,300 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 65,163 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.