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The Wilms’ tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells

Overview of attention for article published in Molecular Cancer, January 2013
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Title
The Wilms’ tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells
Published in
Molecular Cancer, January 2013
DOI 10.1186/1476-4598-12-3
Pubmed ID
Authors

Adina Brett, Sony Pandey, Gail Fraizer

Abstract

One key step in the development of prostate cancer (PCa) metastasis is the loss of E-cadherin expression associated with increased cellular motility and tumor invasion. This loss of E-cadherin expression is also required during normal embryogenesis and similar transcriptional repressors have been identified in both processes. We have previously reported the presence of one such transcription factor, WT1 in high Gleason grade prostate tumor tissues, and its absence in non-neoplastic or benign prostatic hyperplasia tissues.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 3%
United States 1 3%
Belgium 1 3%
Unknown 37 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 25%
Researcher 9 23%
Student > Bachelor 6 15%
Student > Doctoral Student 3 8%
Student > Master 3 8%
Other 5 13%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 35%
Biochemistry, Genetics and Molecular Biology 8 20%
Medicine and Dentistry 6 15%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Immunology and Microbiology 2 5%
Other 3 8%
Unknown 4 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2013.
All research outputs
#18,326,065
of 22,693,205 outputs
Outputs from Molecular Cancer
#1,283
of 1,714 outputs
Outputs of similar age
#219,124
of 282,037 outputs
Outputs of similar age from Molecular Cancer
#27
of 32 outputs
Altmetric has tracked 22,693,205 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,714 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,037 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.