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The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro

Overview of attention for article published in BMC Veterinary Research, January 2013
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Title
The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro
Published in
BMC Veterinary Research, January 2013
DOI 10.1186/1746-6148-9-15
Pubmed ID
Authors

Kevin Marley, Stuart C Helfand, Wade A Edris, John E Mata, Alix I Gitelman, Jan Medlock, Bernard Séguin

Abstract

Osteosarcoma (OS) affects over 8000 dogs/year in the United States. The disease usually arises in the appendicular skeleton and metastasizes to the lung. Dogs with localized appendicular disease benefit from limb amputation and chemotherapy but most die within 6-12 months despite these treatments. Taurolidine, a derivative of taurine, has anti-tumor and anti-angiogenic effects against a variety of cancers. The following in vitro studies tested taurolidine as a candidate for adjuvant therapy for canine OS. Tests for p53 protein status and caspase activity were used to elucidate mechanisms of taurolidine-induced cell death.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
South Africa 1 2%
Unknown 49 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 20%
Student > Postgraduate 10 20%
Other 6 12%
Student > Bachelor 4 8%
Student > Ph. D. Student 3 6%
Other 11 22%
Unknown 7 14%
Readers by discipline Count As %
Medicine and Dentistry 18 35%
Veterinary Science and Veterinary Medicine 17 33%
Agricultural and Biological Sciences 5 10%
Nursing and Health Professions 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 4%
Unknown 7 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2013.
All research outputs
#13,144,039
of 22,693,205 outputs
Outputs from BMC Veterinary Research
#869
of 3,034 outputs
Outputs of similar age
#157,647
of 284,846 outputs
Outputs of similar age from BMC Veterinary Research
#27
of 83 outputs
Altmetric has tracked 22,693,205 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,034 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,846 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.