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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A proposed preventive role for Gamma-hydroxybutyrate (XyremR) in Alzheimer’s disease
|
|---|---|
| Published in |
Alzheimer's Research & Therapy, September 2016
|
| DOI | 10.1186/s13195-016-0205-y |
| Pubmed ID | |
| Authors |
Michel Maitre, Christian Klein, Ayikoe G. Mensah-Nyagan |
| Abstract |
Gamma-hydroxybutyrate (GHB or Xyrem(R)) is frequently used in humans for several clinical indications, including anesthesia, narcolepsy/cataplexy, and alcohol-withdrawal symptoms. Pharmacological effects induced in the brain by therapeutic doses of Xyrem(R) are generally GABAergic-dependent. These effects allow sedation, stress/anxiety reduction, deep sleep induction, decrease of neuroinflammation, and neuroprotection. Furthermore, Xyrem(R) promotes the expression of pivotal genes reducing toxic proteinopathies, as demonstrated in laboratory animal models. Altogether, these data represent additional evidence to suggest that Xyrem(R) may be tested during repeated short periods in populations at risk for Alzheimer's disease. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Bolivia, Plurinational State of | 1 | 17% |
| United Kingdom | 1 | 17% |
| Australia | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 19% |
| Student > Bachelor | 6 | 13% |
| Student > Ph. D. Student | 6 | 13% |
| Student > Postgraduate | 3 | 6% |
| Researcher | 3 | 6% |
| Other | 5 | 10% |
| Unknown | 16 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 7 | 15% |
| Medicine and Dentistry | 6 | 13% |
| Biochemistry, Genetics and Molecular Biology | 4 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Nursing and Health Professions | 3 | 6% |
| Other | 8 | 17% |
| Unknown | 17 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2019.
All research outputs
#2,265,991
of 22,886,568 outputs
Outputs from Alzheimer's Research & Therapy
#501
of 1,235 outputs
Outputs of similar age
#41,803
of 334,695 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#6
of 15 outputs
Altmetric has tracked 22,886,568 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,235 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,695 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.