Title |
Evaluation of Xpert MTB/RIF and MODS assay for the diagnosis of pediatric tuberculosis
|
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Published in |
BMC Infectious Diseases, January 2013
|
DOI | 10.1186/1471-2334-13-31 |
Pubmed ID | |
Authors |
Nguyen Thi Quynh Nhu, Dang Thi Minh Ha, Nguyen Duc Anh, Do Dang Anh Thu, Tran Ngoc Duong, Nguyen Dang Quang, Nguyen Thi Ngoc Lan, Tran Van Quyet, Nguyen Thi Bich Tuyen, Vo Thi Ha, Do Chau Giang, Nguyen Huy Dung, Marcel Wolbers, Jeremy Farrar, Maxine Caws |
Abstract |
Tuberculosis (TB) in children is rarely confirmed due to the lack of effective diagnostic tools; only 10 to 15% of pediatric TB is smear positive due to paucibacillary samples and the difficulty of obtaining high-quality specimens from children. We evaluate here the accuracy of Xpert MTB/RIF in comparison with the Micoroscopic observation drug susceptibility (MODS) assay for diagnosis of TB in children using samples stored during a previously reported evaluation of the MODS assay. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Chile | 1 | 17% |
Mexico | 1 | 17% |
Unknown | 4 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 67% |
Practitioners (doctors, other healthcare professionals) | 2 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Colombia | 2 | 1% |
Netherlands | 1 | <1% |
Australia | 1 | <1% |
Canada | 1 | <1% |
Rwanda | 1 | <1% |
Spain | 1 | <1% |
Unknown | 135 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 24 | 17% |
Student > Ph. D. Student | 23 | 16% |
Student > Master | 18 | 13% |
Student > Postgraduate | 13 | 9% |
Other | 12 | 8% |
Other | 26 | 18% |
Unknown | 26 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 59 | 42% |
Agricultural and Biological Sciences | 16 | 11% |
Immunology and Microbiology | 9 | 6% |
Biochemistry, Genetics and Molecular Biology | 7 | 5% |
Social Sciences | 6 | 4% |
Other | 16 | 11% |
Unknown | 29 | 20% |