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Transcriptome analysis of bitter acid biosynthesis and precursor pathways in hop (Humulus lupulus)

Overview of attention for article published in BMC Plant Biology, January 2013
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  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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6 X users
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1 Facebook page

Citations

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129 Mendeley
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Title
Transcriptome analysis of bitter acid biosynthesis and precursor pathways in hop (Humulus lupulus)
Published in
BMC Plant Biology, January 2013
DOI 10.1186/1471-2229-13-12
Pubmed ID
Authors

Shawn M Clark, Vinidhra Vaitheeswaran, Stephen J Ambrose, Randy W Purves, Jonathan E Page

Abstract

Bitter acids (e.g. humulone) are prenylated polyketides synthesized in lupulin glands of the hop plant (Humulus lupulus) which are important contributors to the bitter flavour and stability of beer. Bitter acids are formed from acyl-CoA precursors derived from branched-chain amino acid (BCAA) degradation and C5 prenyl diphosphates from the methyl-D-erythritol 4-phosphate (MEP) pathway. We used RNA sequencing (RNA-seq) to obtain the transcriptomes of isolated lupulin glands, cones with glands removed and leaves from high α-acid hop cultivars, and analyzed these datasets for genes involved in bitter acid biosynthesis including the supply of major precursors. We also measured the levels of BCAAs, acyl-CoA intermediates, and bitter acids in glands, cones and leaves.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Canada 1 <1%
Unknown 127 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 37 29%
Student > Bachelor 21 16%
Student > Ph. D. Student 20 16%
Student > Master 12 9%
Student > Doctoral Student 7 5%
Other 15 12%
Unknown 17 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 48%
Biochemistry, Genetics and Molecular Biology 23 18%
Chemistry 5 4%
Engineering 5 4%
Environmental Science 2 2%
Other 13 10%
Unknown 19 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2013.
All research outputs
#8,007,542
of 24,079,942 outputs
Outputs from BMC Plant Biology
#675
of 3,392 outputs
Outputs of similar age
#87,919
of 287,756 outputs
Outputs of similar age from BMC Plant Biology
#16
of 55 outputs
Altmetric has tracked 24,079,942 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,392 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,756 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.