Title |
Sustaining remission of psychotic depression: rationale, design and methodology of STOP-PD ΙΙ
|
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Published in |
BMC Psychiatry, January 2013
|
DOI | 10.1186/1471-244x-13-38 |
Pubmed ID | |
Authors |
Alastair J Flint, Barnett S Meyers, Anthony J Rothschild, Ellen M Whyte, Benoit H Mulsant, Matthew V Rudorfer, Patricia Marino |
Abstract |
Psychotic depression (PD) is a severe disabling disorder with considerable morbidity and mortality. Electroconvulsive therapy and pharmacotherapy are each efficacious in the treatment of PD. Expert guidelines recommend the combination of antidepressant and antipsychotic medications in the acute pharmacologic treatment of PD. However, little is known about the continuation treatment of PD. Of particular concern, it is not known whether antipsychotic medication needs to be continued once an episode of PD responds to pharmacotherapy. This issue has profound clinical importance. On the one hand, the unnecessary continuation of antipsychotic medication exposes a patient to adverse effects, such as weight gain and metabolic disturbance. On the other hand, premature discontinuation of antipsychotic medication has the potential risk of early relapse of a severe disorder. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 25% |
Egypt | 1 | 25% |
United States | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 1% |
Japan | 1 | <1% |
United States | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 149 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 22 | 14% |
Student > Bachelor | 16 | 10% |
Student > Postgraduate | 14 | 9% |
Student > Doctoral Student | 14 | 9% |
Researcher | 13 | 8% |
Other | 30 | 19% |
Unknown | 45 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 49 | 32% |
Psychology | 13 | 8% |
Nursing and Health Professions | 10 | 6% |
Neuroscience | 8 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 5% |
Other | 16 | 10% |
Unknown | 50 | 32% |