Title |
A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12
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Published in |
BMC Genomics, January 2013
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DOI | 10.1186/1471-2164-14-55 |
Pubmed ID | |
Authors |
Ceres Fernandez-Rozadilla, Jean-Baptiste Cazier, Ian P Tomlinson, Luis G Carvajal-Carmona, Claire Palles, María J Lamas, Montserrat Baiget, Luis A López-Fernández, Alejandro Brea-Fernández, Anna Abulí, Luis Bujanda, Juan Clofent, Dolors Gonzalez, Rosa Xicola, Montserrat Andreu, Xavier Bessa, Rodrigo Jover, Xavier Llor, The EPICOLON Consortium, Víctor Moreno, Antoni Castells, Ángel Carracedo, Sergi Castellvi-Bel, Clara Ruiz-Ponte |
Abstract |
Colorectal cancer (CRC) is a disease of complex aetiology, with much of the expected inherited risk being due to several common low risk variants. Genome-Wide Association Studies (GWAS) have identified 20 CRC risk variants. Nevertheless, these have only been able to explain part of the missing heritability. Moreover, these signals have only been inspected in populations of Northern European origin. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 67% |
United States | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 4% |
United Kingdom | 1 | 2% |
Uruguay | 1 | 2% |
Unknown | 52 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 21% |
Student > Ph. D. Student | 8 | 14% |
Other | 4 | 7% |
Professor > Associate Professor | 4 | 7% |
Student > Doctoral Student | 4 | 7% |
Other | 10 | 18% |
Unknown | 14 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 16 | 29% |
Agricultural and Biological Sciences | 12 | 21% |
Medicine and Dentistry | 8 | 14% |
Unspecified | 1 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 0 | 0% |
Unknown | 18 | 32% |