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Radiosensitization in prostate cancer: mechanisms and targets

Overview of attention for article published in BMC Urology, January 2013
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2 X users

Citations

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37 Dimensions

Readers on

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63 Mendeley
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Title
Radiosensitization in prostate cancer: mechanisms and targets
Published in
BMC Urology, January 2013
DOI 10.1186/1471-2490-13-4
Pubmed ID
Authors

Diego A Palacios, Makito Miyake, Charles J Rosser

Abstract

Prostate cancer is the second most commonly diagnosed cancer in American men over the age of 45 years and is the third most common cause of cancer related deaths in American men. In 2012 it is estimated that 241,740 men will be diagnosed with prostate cancer and 28,170 men will succumb to prostate cancer. Currently, radiation therapy is one of the most common definitive treatment options for localized prostate cancer. However, significant number of patients undergoing radiation therapy will develop locally persistent/recurrent tumours. The varying response rates to radiation may be due to 1) tumor microenvironment, 2) tumor stage/grade, 3) modality used to deliver radiation, and 4) dose of radiation. Higher doses of radiation has not always proved to be effective and have been associated with increased morbidity. Compounds designed to enhance the killing effects of radiation, radiosensitizers, have been extensively investigated over the past decade. The development of radiosensitizing agents could improve survival, improve quality of life and reduce costs, thus benefiting both patients and healthcare systems. Herin, we shall review the role and mechanisms of various agents that can sensitize tumours, specifically prostate cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Unknown 62 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 32%
Researcher 8 13%
Student > Doctoral Student 7 11%
Student > Master 6 10%
Student > Bachelor 6 10%
Other 4 6%
Unknown 12 19%
Readers by discipline Count As %
Medicine and Dentistry 13 21%
Biochemistry, Genetics and Molecular Biology 11 17%
Agricultural and Biological Sciences 5 8%
Physics and Astronomy 4 6%
Chemistry 4 6%
Other 11 17%
Unknown 15 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2013.
All research outputs
#15,557,505
of 23,881,329 outputs
Outputs from BMC Urology
#383
of 775 outputs
Outputs of similar age
#181,204
of 287,097 outputs
Outputs of similar age from BMC Urology
#5
of 8 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 775 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,097 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.