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Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression

Overview of attention for article published in Respiratory Research, September 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

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1 X user
patent
3 patents
facebook
2 Facebook pages

Citations

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121 Dimensions

Readers on

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106 Mendeley
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Title
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression
Published in
Respiratory Research, September 2010
DOI 10.1186/1465-9921-11-131
Pubmed ID
Authors

Shyamala Ganesan, Andrea N Faris, Adam T Comstock, Sangbrita S Chattoraj, Asamanja Chattoraj, John R Burgess, Jeffrey L Curtis, Fernando J Martinez, Suzanna Zick, Marc B Hershenson, Uma S Sajjan

Abstract

Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases. Quercetin, a plant flavonoid, is a potent antioxidant and anti-inflammatory agent. We hypothesized that quercetin reduces lung inflammation and improves lung function in elastase/lipopolysaccharide (LPS)-exposed mice which show typical features of COPD, including airways inflammation, goblet cell metaplasia, and emphysema.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Australia 1 <1%
Unknown 103 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 16%
Student > Doctoral Student 10 9%
Researcher 9 8%
Student > Bachelor 8 8%
Other 6 6%
Other 27 25%
Unknown 29 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 24%
Medicine and Dentistry 19 18%
Biochemistry, Genetics and Molecular Biology 11 10%
Pharmacology, Toxicology and Pharmaceutical Science 6 6%
Immunology and Microbiology 4 4%
Other 11 10%
Unknown 30 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2023.
All research outputs
#4,659,861
of 25,374,917 outputs
Outputs from Respiratory Research
#582
of 3,062 outputs
Outputs of similar age
#20,073
of 107,943 outputs
Outputs of similar age from Respiratory Research
#4
of 20 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 107,943 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.