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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells
|
|---|---|
| Published in |
Journal of Neuroinflammation, January 2013
|
| DOI | 10.1186/1742-2094-10-15 |
| Pubmed ID | |
| Authors |
Dennis Y Chuang, Ming-Huan Chan, Yijia Zong, Wenwen Sheng, Yan He, Jing Hua Jiang, Agnes Simonyi, Zezong Gu, Kevin L Fritsche, Jiankun Cui, James C Lee, William R Folk, Dennis B Lubahn, Albert Y Sun, Grace Y Sun |
| Abstract |
The bark of magnolia has been used in Oriental medicine to treat a variety of remedies, including some neurological disorders. Magnolol (Mag) and honokiol (Hon) are isomers of polyphenolic compounds from the bark of Magnolia officinalis, and have been identified as major active components exhibiting anti-oxidative, anti-inflammatory, and neuroprotective effects. In this study, we investigate the ability of these isomers to suppress oxidative stress in neurons stimulated by the ionotropic glutamate receptor agonist N-methyl-D-aspartate (NMDA) and oxidative and inflammatory responses in microglial cells activated by interferon-γ (IFNγ) and lipopolysaccharide (LPS). We also attempt to elucidate the mechanism and signaling pathways involved in cytokine-induced production of reactive oxygen species (ROS) in microglial cells. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| United Kingdom | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 77 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 18% |
| Student > Ph. D. Student | 12 | 15% |
| Student > Bachelor | 9 | 11% |
| Student > Master | 9 | 11% |
| Other | 6 | 8% |
| Other | 8 | 10% |
| Unknown | 21 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 22% |
| Medicine and Dentistry | 10 | 13% |
| Neuroscience | 10 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 6% |
| Nursing and Health Professions | 3 | 4% |
| Other | 6 | 8% |
| Unknown | 28 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2023.
All research outputs
#2,189,708
of 24,268,934 outputs
Outputs from Journal of Neuroinflammation
#274
of 2,797 outputs
Outputs of similar age
#22,187
of 290,985 outputs
Outputs of similar age from Journal of Neuroinflammation
#2
of 31 outputs
Altmetric has tracked 24,268,934 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,797 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,985 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.