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Passive transfer of collagen XVII-specific antibodies induces sustained blistering disease in adult mice

Overview of attention for article published in Orphanet Journal of Rare Diseases, January 2013
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Title
Passive transfer of collagen XVII-specific antibodies induces sustained blistering disease in adult mice
Published in
Orphanet Journal of Rare Diseases, January 2013
DOI 10.1186/1750-1172-8-17
Pubmed ID
Authors

Mircea Teodor Chiriac, Emilia Licarete, Alexandra Gabriela Sas, Andreea Maria Rados, Iulia Lupan, Anca Mirela Chiriac, Hilda Speth, Vlad Pop-Vancia, Iacob Domsa, Alina Sesarman, Octavian Popescu, Cassian Sitaru

Abstract

Bullous pemphigoid is a subepidermal blistering disorder associated with tissue-bound and circulating autoantibodies directed mainly to the hemidesmosomal component collagen XVII. While recapitulating the main immunopathological features of the human disease, frank skin blistering does not develop in the absence of skin rubbing in experimental pemphigoid models that have been established in neonatal mice. Moreover, due to their experimental design they only allow for short-term disease observation. In the present study we aimed to establish a model that reproduces the frank skin blistering seen in patients and allows for longer observation times.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 38%
Researcher 3 14%
Student > Postgraduate 2 10%
Professor 1 5%
Professor > Associate Professor 1 5%
Other 1 5%
Unknown 5 24%
Readers by discipline Count As %
Medicine and Dentistry 6 29%
Agricultural and Biological Sciences 3 14%
Immunology and Microbiology 3 14%
Biochemistry, Genetics and Molecular Biology 2 10%
Chemistry 1 5%
Other 0 0%
Unknown 6 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2013.
All research outputs
#13,376,862
of 22,694,633 outputs
Outputs from Orphanet Journal of Rare Diseases
#1,379
of 2,599 outputs
Outputs of similar age
#158,675
of 282,817 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#60
of 92 outputs
Altmetric has tracked 22,694,633 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,599 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,817 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.