Title |
Host iron redistribution as a risk factor for incident tuberculosis in HIV infection: an 11-year retrospective cohort study
|
---|---|
Published in |
BMC Infectious Diseases, January 2013
|
DOI | 10.1186/1471-2334-13-48 |
Pubmed ID | |
Authors |
Joann M McDermid, Branwen J Hennig, Marianne van der Sande, Adrian VS Hill, Hilton C Whittle, Assan Jaye, Andrew M Prentice |
Abstract |
Identifying people at higher risk of developing tuberculosis with human immunodeficiency virus (HIV) infection may improve clinical management of co-infections. Iron influences tuberculosis (TB) pathogenesis, but understanding the exact mechanisms of how and timing of when iron is involved remains challenging since biological samples are rarely available from the disease susceptibility period due to the difficulty in predicting in who and when, if ever, TB will develop. The objective of this research was to determine how host iron status measured at HIV diagnosis and genotypes related to host iron metabolism were associated with incident TB. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
Italy | 1 | <1% |
Zimbabwe | 1 | <1% |
Egypt | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 144 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 24 | 16% |
Researcher | 24 | 16% |
Student > Master | 18 | 12% |
Student > Bachelor | 13 | 9% |
Student > Postgraduate | 10 | 7% |
Other | 28 | 19% |
Unknown | 33 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 36 | 24% |
Agricultural and Biological Sciences | 32 | 21% |
Biochemistry, Genetics and Molecular Biology | 11 | 7% |
Nursing and Health Professions | 9 | 6% |
Social Sciences | 7 | 5% |
Other | 15 | 10% |
Unknown | 40 | 27% |