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A computational framework for gene regulatory network inference that combines multiple methods and datasets

Overview of attention for article published in BMC Systems Biology, April 2011
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Title
A computational framework for gene regulatory network inference that combines multiple methods and datasets
Published in
BMC Systems Biology, April 2011
DOI 10.1186/1752-0509-5-52
Pubmed ID
Authors

Rita Gupta, Anna Stincone, Philipp Antczak, Sarah Durant, Roy Bicknell, Andreas Bikfalvi, Francesco Falciani

Abstract

Reverse engineering in systems biology entails inference of gene regulatory networks from observational data. This data typically include gene expression measurements of wild type and mutant cells in response to a given stimulus. It has been shown that when more than one type of experiment is used in the network inference process the accuracy is higher. Therefore the development of generally applicable and effective methodologies that embed multiple sources of information in a single computational framework is a worthwhile objective.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
France 2 2%
Denmark 2 2%
United Kingdom 2 2%
Brazil 1 <1%
Sweden 1 <1%
Latvia 1 <1%
India 1 <1%
Ukraine 1 <1%
Other 0 0%
Unknown 92 87%

Demographic breakdown

Readers by professional status Count As %
Researcher 30 28%
Student > Ph. D. Student 26 25%
Student > Master 15 14%
Professor > Associate Professor 8 8%
Other 6 6%
Other 15 14%
Unknown 6 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 41 39%
Computer Science 24 23%
Biochemistry, Genetics and Molecular Biology 10 9%
Environmental Science 4 4%
Engineering 3 3%
Other 12 11%
Unknown 12 11%