Title |
Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report
|
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Published in |
Malaria Journal, September 2016
|
DOI | 10.1186/s12936-016-1527-8 |
Pubmed ID | |
Authors |
Arnaud Chêne, Sophie Houard, Morten A. Nielsen, Sophia Hundt, Flavia D’Alessio, Sodiomon B. Sirima, Adrian J. F. Luty, Patrick Duffy, Odile Leroy, Benoit Gamain, Nicola K. Viebig |
Abstract |
Placental malaria caused by Plasmodium falciparum infection constitutes a major health problem manifesting as severe disease and anaemia in the mother, impaired fetal development, low birth weight or spontaneous abortion. Prevention of placental malaria currently relies on two key strategies that are losing efficacy due to spread of resistance: long-lasting insecticide-treated nets and intermittent preventive treatment during pregnancy. A placental malaria vaccine would be an attractive, cost-effective complement to the existing control tools. Two placental malaria vaccine candidates are currently in Phase Ia/b clinical trials. During two workshops hosted by the European Vaccine Initiative, one in Paris in April 2014 and the other in Brussels in November 2014, the main actors in placental malaria vaccine research discussed the harmonization of clinical development plans and of the immunoassays with a goal to define standards that will allow comparative assessment of different placental malaria vaccine candidates. The recommendations of these workshops should guide researchers and clinicians in the further development of placental malaria vaccines. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 25% |
Belgium | 1 | 13% |
Unknown | 5 | 63% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 63% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Belgium | 1 | 1% |
Unknown | 92 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 17 | 18% |
Student > Ph. D. Student | 15 | 16% |
Researcher | 12 | 13% |
Student > Bachelor | 5 | 5% |
Student > Doctoral Student | 3 | 3% |
Other | 11 | 12% |
Unknown | 31 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 15% |
Biochemistry, Genetics and Molecular Biology | 9 | 10% |
Agricultural and Biological Sciences | 8 | 9% |
Immunology and Microbiology | 8 | 9% |
Nursing and Health Professions | 7 | 7% |
Other | 15 | 16% |
Unknown | 33 | 35% |