Title |
Accounting for the increase in NSAID expenditure: substitution or leakage?
|
---|---|
Published in |
Cost Effectiveness and Resource Allocation, May 2006
|
DOI | 10.1186/1478-7547-4-9 |
Pubmed ID | |
Authors |
Garry R Barton, Anthony J Avery, David K Whynes |
Abstract |
National Institute of Health and Clinical Excellence (NICE) guidance stated that a new form of non-steroidal anti-inflammatory drug (NSAID) (selective COX-2 inhibitors) should only be an option for arthritis patients at high risk of a gastro-intestinal (GI) event. Total expenditure on NSAIDs has risen by 57% over five years, to 247 pounds sterling million in 2004. We assess whether this expenditure increase can be accounted for by substitution--an increased prescribing of two (more expensive) selective COX-2 inhibitors (celecoxib and rofecoxib) and a simultaneous equivalent reduction in the prescribing volume of three (cheaper) older NSAIDs (diclofenac, ibuprofen and naproxen). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 2 | 13% |
Unknown | 14 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 38% |
Student > Ph. D. Student | 3 | 19% |
Student > Doctoral Student | 1 | 6% |
Student > Master | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 2 | 13% |
Unknown | 2 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 44% |
Agricultural and Biological Sciences | 2 | 13% |
Environmental Science | 1 | 6% |
Business, Management and Accounting | 1 | 6% |
Economics, Econometrics and Finance | 1 | 6% |
Other | 1 | 6% |
Unknown | 3 | 19% |