Title |
Dedifferentiated chondrosarcoma of the cervical spine: a case report
|
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Published in |
World Journal of Surgical Oncology, February 2013
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DOI | 10.1186/1477-7819-11-32 |
Pubmed ID | |
Authors |
Yoshihiro Matsumoto, Yusuke Takahashi, Katsumi Harimaya, Takeshi Nakagawa, Kenichi Kawaguchi, Seiji Okada, Mitsumasa Hayashida, Toshio Doi, Akio Sakamoto, Tomoya Matsunobu, Yoshinao Oda, Yukihide Iwamoto |
Abstract |
Dedifferentiated chondrosarcoma (DDCS) is a rare and aggressive bone tumor with poor prognosis. Primary DDCS of the mobile spine is extremely rare, particularly in the cervical spine. We herein describe a first case of cervical DDCS in an 81-year-old male presenting with a slowly growing mass. Radiographs showed an expansion of the cortical contour of the C2 lamina and a soft tissue mass with punctate calcification. Magnetic resonance imaging demonstrated a lobulated lesion expanding over the entire lamina and pedicles of C2 with the tumor protuberant to the adjacent soft tissue. A complete tumor resection was performed. Histologically, the majority of the tumor was a low-grade chondrosarcoma component. However, atypical spindle cells that had proliferated in a fascicular pattern with a collagenous stroma, mimicking fibrosarcoma, were focally observed without a transitional zone, and these features confirmed that the tumor was DDCS. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
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Italy | 1 | 8% |
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Demographic breakdown
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Researcher | 2 | 15% |
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Student > Master | 1 | 8% |
Other | 1 | 8% |
Other | 2 | 15% |
Unknown | 1 | 8% |
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Unknown | 3 | 23% |