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X Demographics
Mendeley readers
| Title |
MST1, a key player, in enhancing fast skeletal muscle atrophy
|
|---|---|
| Published in |
BMC Biology, February 2013
|
| DOI | 10.1186/1741-7007-11-12 |
| Pubmed ID | |
| Authors |
Bin Wei, Wen Dui, Dong Liu, Yan Xing, Zengqiang Yuan, Guangju Ji |
| Abstract |
Skeletal muscle undergoes rapid atrophy upon denervation and the underlying mechanisms are complicated. FOXO3a has been implicated as a major mediator of muscle atrophy, but how its subcellular location and activity is controlled during the pathogenesis of muscle atrophy remains largely unknown. MST1 (Mammalian Sterile 20-like kinase 1) is identified as a central component of the Hippo signaling pathway. MST1 has been shown to mediate phosphorylation of FOXO3a at Ser207. Whether this MST1-FOXO signaling cascade exerts any functional consequence on cellular homeostasis remains to be investigated. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 69 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 23% |
| Student > Ph. D. Student | 13 | 19% |
| Student > Master | 7 | 10% |
| Student > Postgraduate | 5 | 7% |
| Professor | 4 | 6% |
| Other | 14 | 20% |
| Unknown | 10 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 30% |
| Agricultural and Biological Sciences | 21 | 30% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Nursing and Health Professions | 3 | 4% |
| Medicine and Dentistry | 3 | 4% |
| Other | 6 | 9% |
| Unknown | 12 | 17% |