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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Epigenetic mechanisms in migraine: a promising avenue?
|
|---|---|
| Published in |
BMC Medicine, February 2013
|
| DOI | 10.1186/1741-7015-11-26 |
| Pubmed ID | |
| Authors |
Else Eising, Nicole A Datson, Arn MJM van den Maagdenberg, Michel D Ferrari |
| Abstract |
Migraine is a disabling common brain disorder typically characterized by attacks of severe headache and associated with autonomic and neurological symptoms. Its etiology is far from resolved. This review will focus on evidence that epigenetic mechanisms play an important role in disease etiology. Epigenetics comprise both DNA methylation and post-translational modifications of the tails of histone proteins, affecting chromatin structure and gene expression. Besides playing a role in establishing cellular and developmental stage-specific regulation of gene expression, epigenetic processes are also important for programming lasting cellular responses to environmental signals. Epigenetic mechanisms may explain how non-genetic endogenous and exogenous factors such as female sex hormones, stress hormones and inflammation trigger may modulate attack frequency. Developing drugs that specifically target epigenetic mechanisms may open up exciting new avenues for the prophylactic treatment of migraine. |
X Demographics
The data shown below were collected from the profiles of 29 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 28% |
| United Kingdom | 5 | 17% |
| Spain | 2 | 7% |
| Venezuela, Bolivarian Republic of | 1 | 3% |
| Mexico | 1 | 3% |
| Germany | 1 | 3% |
| Canada | 1 | 3% |
| Australia | 1 | 3% |
| Unknown | 9 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 21 | 72% |
| Practitioners (doctors, other healthcare professionals) | 5 | 17% |
| Science communicators (journalists, bloggers, editors) | 2 | 7% |
| Scientists | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | <1% |
| Brazil | 1 | <1% |
| South Africa | 1 | <1% |
| Denmark | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 116 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 17% |
| Researcher | 19 | 16% |
| Student > Bachelor | 16 | 13% |
| Student > Master | 13 | 11% |
| Other | 9 | 7% |
| Other | 23 | 19% |
| Unknown | 20 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 38 | 31% |
| Neuroscience | 17 | 14% |
| Biochemistry, Genetics and Molecular Biology | 13 | 11% |
| Agricultural and Biological Sciences | 9 | 7% |
| Nursing and Health Professions | 7 | 6% |
| Other | 13 | 11% |
| Unknown | 24 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 89. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2020.
All research outputs
#445,700
of 24,172,513 outputs
Outputs from BMC Medicine
#343
of 3,694 outputs
Outputs of similar age
#3,495
of 290,826 outputs
Outputs of similar age from BMC Medicine
#9
of 81 outputs
Altmetric has tracked 24,172,513 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,694 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,826 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.