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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Precision medicine: from pharmacogenomics to pharmacoproteomics
|
|---|---|
| Published in |
Clinical Proteomics, September 2016
|
| DOI | 10.1186/s12014-016-9127-8 |
| Pubmed ID | |
| Authors |
Allison B. Chambliss, Daniel W. Chan |
| Abstract |
Disease progression and drug response may vary significantly from patient to patient. Fortunately, the rapid development of high-throughput 'omics' technologies has allowed for the identification of potential biomarkers that may aid in the understanding of the heterogeneities in disease development and treatment outcomes. However, mechanistic gaps remain when the genome or the proteome are investigated independently in response to drug treatment. In this article, we discuss the current status of pharmacogenomics in precision medicine and highlight the needs for concordant analysis at the proteome and metabolome levels via the more recently-evolved fields of pharmacoproteomics, toxicoproteomics, and pharmacometabolomics. Integrated 'omics' investigations will be critical in piecing together targetable mechanisms of action for both drug development and monitoring of therapy in order to fully apply precision medicine to the clinic. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 29% |
| United Kingdom | 1 | 14% |
| Germany | 1 | 14% |
| Unknown | 3 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Scientists | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 108 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 15 | 14% |
| Researcher | 14 | 13% |
| Student > Ph. D. Student | 13 | 12% |
| Student > Bachelor | 11 | 10% |
| Other | 8 | 7% |
| Other | 19 | 17% |
| Unknown | 29 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 24 | 22% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 12% |
| Engineering | 9 | 8% |
| Medicine and Dentistry | 9 | 8% |
| Agricultural and Biological Sciences | 9 | 8% |
| Other | 11 | 10% |
| Unknown | 34 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2018.
All research outputs
#6,309,205
of 22,889,074 outputs
Outputs from Clinical Proteomics
#78
of 285 outputs
Outputs of similar age
#97,277
of 322,700 outputs
Outputs of similar age from Clinical Proteomics
#3
of 15 outputs
Altmetric has tracked 22,889,074 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 285 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,700 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.