If you have traumatic brain injury do not take checkpoint inhibitors ...they will overcome the beneficial effects of PD-L1 found on #astrocytes https://t.co/xT2eFGrhH1
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24,626 followers
Reactive astrocytes possess potent immune suppressive effects by expression of the prototypic checkpoint PD-L1 https://t.co/xT2eFGqJRt
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PD-L1 signaling in reactive astrocytes counteracts neuroinflammation and ameliorates neuronal damage after traumatic brain injury https://t.co/SyHqWDxk4e
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RT @davidjloane: PD-L1+ astrocytes act as a gatekeeper to control TBI-related neuroimmune and neuroinflammatory responses #TBI #jneuroinfla…