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Salvage surgery for local failures after stereotactic ablative radiotherapy for early stage non-small cell lung cancer

Overview of attention for article published in Radiation Oncology, October 2016
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  • High Attention Score compared to outputs of the same age and source (84th percentile)

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Citations

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29 Dimensions

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33 Mendeley
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Title
Salvage surgery for local failures after stereotactic ablative radiotherapy for early stage non-small cell lung cancer
Published in
Radiation Oncology, October 2016
DOI 10.1186/s13014-016-0706-7
Pubmed ID
Authors

Naomi E. Verstegen, Alexander P. W. M. Maat, Frank J. Lagerwaard, Marinus A. Paul, Michel I Versteegh, Joris J. Joosten, Willem Lastdrager, Egbert F. Smit, Ben J. Slotman, Joost J. M. E. Nuyttens, Suresh Senan

Abstract

The literature on surgical salvage, i.e. lung resections in patients who develop a local recurrence following stereotactic ablative radiotherapy (SABR), is limited. We describe our experience with salvage surgery in nine patients who developed a local recurrence following SABR for early stage non-small cell lung cancer (NSCLC). Patients who underwent surgical salvage for a local recurrence following SABR for NSCLC were identified from two Dutch institutional databases. Complications were scored using the Dindo-Clavien-classification. Nine patients who underwent surgery for a local recurrence were identified. Median time to local recurrence was 22 months. Recurrences were diagnosed with CT- and/or 18FDG-PET-imaging, with four patients also having a pre-surgical pathological diagnosis. Extensive adhesions were observed during two resections, requiring conversion from a thoracoscopic procedure to thoracotomy during one of these procedures. Three patients experienced complications post-surgery; grade 2 (N = 2) and grade 3a (N = 1), respectively. All resection specimens showed viable tumor cells. Median length of hospital stay was 8 days (range 5-15 days) and 30-day mortality was 0 %. Lymph node dissection revealed mediastinal metastases in 3 patients, all of whom received adjuvant therapy. Our experience with nine surgical procedures for local recurrences post-SABR revealed two grade IIIa complications, and a 30-day mortality of 0 %, suggesting that salvage surgery can be safely performed after SABR.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 12%
Other 4 12%
Professor 3 9%
Student > Master 3 9%
Student > Postgraduate 2 6%
Other 7 21%
Unknown 10 30%
Readers by discipline Count As %
Medicine and Dentistry 13 39%
Psychology 2 6%
Linguistics 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Nursing and Health Professions 1 3%
Other 0 0%
Unknown 15 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2016.
All research outputs
#13,480,516
of 22,890,496 outputs
Outputs from Radiation Oncology
#654
of 2,060 outputs
Outputs of similar age
#169,574
of 321,456 outputs
Outputs of similar age from Radiation Oncology
#7
of 44 outputs
Altmetric has tracked 22,890,496 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,060 research outputs from this source. They receive a mean Attention Score of 2.7. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,456 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.