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Reduced viral burden in paralytic compared to furious canine rabies is associated with prominent inflammation at the brainstem level

Overview of attention for article published in BMC Veterinary Research, February 2013
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73 Mendeley
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Title
Reduced viral burden in paralytic compared to furious canine rabies is associated with prominent inflammation at the brainstem level
Published in
BMC Veterinary Research, February 2013
DOI 10.1186/1746-6148-9-31
Pubmed ID
Authors

Shanop Shuangshoti, Nischol Thepa, Pornchai Phukpattaranont, Akanitt Jittmittraphap, Nirun Intarut, Veera Tepsumethanon, Supaporn Wacharapluesadee, Paul Scott Thorner, Thiravat Hemachudha

Abstract

The mechanisms that differentiate rabies infections into furious and paralytic forms remain undetermined. There are no neuropathological features in human brains that distinguish furious and paralytic rabies. This could be due to methodology and/or examination of specimens late in the disease course.In this study, postmortem examination of brain (5 furious and 5 paralytic) and spinal cord (3 furious and 3 paralytic) specimens was performed in 10 rabies-infected dogs, sacrificed shortly after developing the illness. Rabies virus (RABV) antigen (percentage of positive neurons, average antigen area in positive neurons and average antigen area per neuron) and RNA were quantified at 15 different central nervous system (CNS) regions. The distribution and degree of inflammation were also studied.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 2 3%
Unknown 71 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 15%
Student > Master 11 15%
Student > Bachelor 10 14%
Student > Ph. D. Student 6 8%
Other 4 5%
Other 11 15%
Unknown 20 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 26%
Veterinary Science and Veterinary Medicine 17 23%
Medicine and Dentistry 7 10%
Biochemistry, Genetics and Molecular Biology 2 3%
Nursing and Health Professions 2 3%
Other 7 10%
Unknown 19 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2013.
All research outputs
#16,099,609
of 23,881,329 outputs
Outputs from BMC Veterinary Research
#1,471
of 3,087 outputs
Outputs of similar age
#191,386
of 293,167 outputs
Outputs of similar age from BMC Veterinary Research
#50
of 83 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,087 research outputs from this source. They receive a mean Attention Score of 4.2. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 293,167 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.