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TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm

Overview of attention for article published in Retrovirology, February 2013
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2 X users

Citations

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117 Mendeley
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Title
TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm
Published in
Retrovirology, February 2013
DOI 10.1186/1742-4690-10-20
Pubmed ID
Authors

Alberto De Iaco, Federico Santoni, Anne Vannier, Michel Guipponi, Stylianos Antonarakis, Jeremy Luban

Abstract

Despite intensive investigation the mechanism by which HIV-1 reaches the host cell nucleus is unknown. TNPO3, a karyopherin mediating nuclear entry of SR-proteins, was shown to be required for HIV-1 infectivity. Some investigators have reported that TNPO3 promotes HIV-1 nuclear import, as would be expected for a karyopherin. Yet, an equal number of investigators have failed to obtain evidence that supports this model. Here, a series of experiments were performed to better elucidate the mechanism by which TNPO3 promotes HIV-1 infectivity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 <1%
Italy 1 <1%
Switzerland 1 <1%
Unknown 112 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 35%
Researcher 20 17%
Student > Bachelor 12 10%
Student > Master 9 8%
Student > Doctoral Student 8 7%
Other 9 8%
Unknown 18 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 38 32%
Biochemistry, Genetics and Molecular Biology 31 26%
Immunology and Microbiology 12 10%
Medicine and Dentistry 9 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 5 4%
Unknown 20 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2013.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Retrovirology
#1,025
of 1,273 outputs
Outputs of similar age
#235,060
of 309,585 outputs
Outputs of similar age from Retrovirology
#17
of 24 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,585 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.