Title |
Molecular basis of human cerebral malaria development
|
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Published in |
Tropical Medicine and Health, September 2016
|
DOI | 10.1186/s41182-016-0033-6 |
Pubmed ID | |
Authors |
Saw Thu Wah, Hathairad Hananantachai, Usanee Kerdpin, Chotiros Plabplueng, Virapong Prachayasittikul, Pornlada Nuchnoi |
Abstract |
Cerebral malaria is still a deleterious health problem in tropical countries. The wide spread of malarial drug resistance and the lack of an effective vaccine are obstacles for disease management and prevention. Parasite and human genetic factors play important roles in malaria susceptibility and disease severity. The malaria parasite exerted a potent selective signature on the human genome, which is apparent in the genetic polymorphism landscape of genes related to pathogenesis. Currently, much genomic data and a novel body of knowledge, including the identification of microRNAs, are being increasingly accumulated for the development of laboratory testing cassettes for cerebral malaria prevention. Therefore, understanding of the underlying complex molecular basis of cerebral malaria is important for the design of strategy for cerebral malaria treatment and control. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Belgium | 1 | 25% |
India | 1 | 25% |
Brazil | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Scientists | 1 | 25% |
Members of the public | 1 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 1% |
Unknown | 84 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 18% |
Student > Bachelor | 15 | 18% |
Researcher | 8 | 9% |
Student > Ph. D. Student | 8 | 9% |
Student > Postgraduate | 5 | 6% |
Other | 12 | 14% |
Unknown | 22 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 14 | 16% |
Immunology and Microbiology | 12 | 14% |
Medicine and Dentistry | 12 | 14% |
Agricultural and Biological Sciences | 11 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Other | 7 | 8% |
Unknown | 25 | 29% |