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Genetic variability and spatial distribution in small geographic scale of Aedes aegypti (Diptera: Culicidae) under different climatic conditions in Northeastern Brazil

Overview of attention for article published in Parasites & Vectors, October 2016
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Title
Genetic variability and spatial distribution in small geographic scale of Aedes aegypti (Diptera: Culicidae) under different climatic conditions in Northeastern Brazil
Published in
Parasites & Vectors, October 2016
DOI 10.1186/s13071-016-1814-9
Pubmed ID
Authors

Lizandra Makowski Steffler, Silvio Santana Dolabella, Paulo Eduardo Martins Ribolla, Carine Spenassatto Dreyer, Edilson Divino Araújo, Rosane Gomes Oliveira, Walter Fabrício Silva Martins, Roseli La Corte

Abstract

The study of the genetic structure of Aedes aegypti is essential to understanding their population dynamics as well as for the analysis of factors responsible for their resistance and ecological adaptation. The use of molecular markers in identifying differences amongst populations of Ae. aegypti in different geographical areas as well as the temporal variation of the vector populations has contributed to the improvement of vector control strategies. The present study aims to determine the genetic variability of Ae. aegypti populations in a small geographical area (state of Sergipe, Northeastern Brazil) by means of inter-simple sequence repeat (ISSR) and single nucleotide polymorphism (SNP) molecular markers. ISSR markers revealed a more heterogeneous pattern of genetic diversity among the populations with an expected heterozygosity (H E) ranging from 0.261 ± 0.03 to 0.120 ± 0.032, while a similar trend was detected through SNPs across populations with an H E between 0.375 ± 0.054 and 0.269 ± 0.042. The population's genetic differentiation assessed with ISSR and SNP markers indicated a very low structuring among the populations with the highest diversity observed within the populations 72 % (ISSR) and 92 % (SNP). Clustering analysis also suggested little variation among populations: the seven populations were grouped into only three ISSR clusters and a single panmictic group based on SNP markers. The present study identified a close relationship between the populations, which probably results mainly from passive gene flow between mosquitoes from distinct geographic regions, influenced by humans commuting along roads. There was an intense migration of mosquitos across municipalities, leading to a potential increase in risk of arbovirus and insecticide resistance associated-alleles spreading between mosquito populations.

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The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
United States 1 <1%
Unknown 130 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 17%
Student > Master 19 14%
Student > Ph. D. Student 16 12%
Student > Bachelor 12 9%
Student > Doctoral Student 9 7%
Other 28 21%
Unknown 27 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 22%
Biochemistry, Genetics and Molecular Biology 23 17%
Medicine and Dentistry 10 8%
Immunology and Microbiology 8 6%
Nursing and Health Professions 7 5%
Other 23 17%
Unknown 33 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2017.
All research outputs
#8,693,662
of 25,757,133 outputs
Outputs from Parasites & Vectors
#2,140
of 6,078 outputs
Outputs of similar age
#121,282
of 328,721 outputs
Outputs of similar age from Parasites & Vectors
#35
of 100 outputs
Altmetric has tracked 25,757,133 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,078 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,721 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 100 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.