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Analyzing miRNA co-expression networks to explore TF-miRNA regulation

Overview of attention for article published in BMC Bioinformatics, May 2009
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Citations

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Title
Analyzing miRNA co-expression networks to explore TF-miRNA regulation
Published in
BMC Bioinformatics, May 2009
DOI 10.1186/1471-2105-10-163
Pubmed ID
Authors

Sanghamitra Bandyopadhyay, Malay Bhattacharyya

Abstract

Current microRNA (miRNA) research in progress has engendered rapid accumulation of expression data evolving from microarray experiments. Such experiments are generally performed over different tissues belonging to a specific species of metazoan. For disease diagnosis, microarray probes are also prepared with tissues taken from similar organs of different candidates of an organism. Expression data of miRNAs are frequently mapped to co-expression networks to study the functions of miRNAs, their regulation on genes and to explore the complex regulatory network that might exist between Transcription Factors (TFs), genes and miRNAs. These directions of research relating miRNAs are still not fully explored, and therefore, construction of reliable and compatible methods for mining miRNA co-expression networks has become an emerging area. This paper introduces a novel method for mining the miRNA co-expression networks in order to obtain co-expressed miRNAs under the hypothesis that these might be regulated by common TFs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Brazil 2 2%
Germany 1 <1%
Australia 1 <1%
Sweden 1 <1%
Norway 1 <1%
Mexico 1 <1%
India 1 <1%
Russia 1 <1%
Other 1 <1%
Unknown 110 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 39 32%
Student > Ph. D. Student 25 20%
Professor > Associate Professor 13 11%
Professor 10 8%
Student > Master 8 7%
Other 22 18%
Unknown 6 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 71 58%
Biochemistry, Genetics and Molecular Biology 13 11%
Medicine and Dentistry 11 9%
Computer Science 10 8%
Engineering 3 2%
Other 8 7%
Unknown 7 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2013.
All research outputs
#15,263,666
of 22,696,971 outputs
Outputs from BMC Bioinformatics
#5,362
of 7,254 outputs
Outputs of similar age
#96,913
of 113,629 outputs
Outputs of similar age from BMC Bioinformatics
#27
of 36 outputs
Altmetric has tracked 22,696,971 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,254 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,629 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.