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Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China

Overview of attention for article published in BMC Infectious Diseases, October 2016
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Title
Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China
Published in
BMC Infectious Diseases, October 2016
DOI 10.1186/s12879-016-1840-4
Pubmed ID
Authors

Hui Wang, XinCai Xiao, Jianyun Lu, Zongqiu Chen, Kuibiao Li, Hui Liu, Lei Luo, Ming Wang, ZhiCong Yang

Abstract

Guangzhou reported its first laboratory-confirmed case of influenza A (H7N9) on January 10, 2014. A total of 25 cases were reported from the first wave of the epidemic until April 8, 2014. The fatality rate was much higher than in previous reports. The objective of the current work was to describe the clinical and epidemiological characteristics of A (H7N9) patients in Guangzhou and explore possible reasons for the high fatality rate. Clinical and epidemiological information regarding A (H7N9) cases in Guangzhou was collected through review of medical records and field research. Data regarding clinical and laboratory features, treatment, and outcomes were extracted. Of the 25 patients, 84 % (21/25) had one or more underlying diseases. Fifteen patients (60.0 %) developed moderate to severe acute respiratory distress syndrome (ARDS), and 14 (56 %) died of the ARDS or multiorgan failure. Patients with longer delay between onset of illness and initiation of oseltamivir treatment were more likely to develop ARDS. Elevated C-creative protein, aspartate aminotransferase, creatine kinase, and lymphocytopenia predicted a higher risk of developing ARDS. The presence of underlying diseases and clinical complications predicted poor clinical outcome. Early oseltamivir treatment was associated with a reduced risk of developing ARDS.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 59 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 17%
Student > Master 8 14%
Student > Ph. D. Student 5 8%
Student > Bachelor 5 8%
Other 4 7%
Other 12 20%
Unknown 15 25%
Readers by discipline Count As %
Medicine and Dentistry 18 31%
Nursing and Health Professions 6 10%
Biochemistry, Genetics and Molecular Biology 4 7%
Agricultural and Biological Sciences 4 7%
Immunology and Microbiology 2 3%
Other 7 12%
Unknown 18 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 October 2016.
All research outputs
#20,344,065
of 22,890,496 outputs
Outputs from BMC Infectious Diseases
#6,483
of 7,691 outputs
Outputs of similar age
#278,358
of 321,456 outputs
Outputs of similar age from BMC Infectious Diseases
#176
of 221 outputs
Altmetric has tracked 22,890,496 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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We're also able to compare this research output to 221 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.