Reductive TCA cycle catalyzed by wild-type IDH2 promotes acute myeloid leukemia and is a metabolic vulnerability for potential targeted therapy

Overview of attention for article published in Journal of Hematology & Oncology, March 2022

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Latest findings in #Cancer #Bioenergetics thank to @BiomedNew https://t.co/cDNrZ2kzR8. Lab pick is from @BioMedCentral where the authors link wt-IDH2 to reductive carboxylation that is necessary for AML survival and engraftment in AML https://t.co/ms9r95

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