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DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition

Overview of attention for article published in Retrovirology, February 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

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6 X users

Citations

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29 Dimensions

Readers on

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53 Mendeley
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Title
DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition
Published in
Retrovirology, February 2013
DOI 10.1186/1742-4690-10-21
Pubmed ID
Authors

Takayoshi Koyama, Binlian Sun, Kenzo Tokunaga, Masashi Tatsumi, Yukihito Ishizaka

Abstract

The prevention of persistent human immunodeficiency virus type 1 (HIV-1) infection requires the clarification of the mode of viral transduction into resting macrophages. Recently, DNA double-strand breaks (DSBs) were shown to enhance infection by D64A virus, which has a defective integrase catalytic activity (IN-CA). However, the mechanism by which DSBs upregulate viral transduction was unclear. Here we analyzed the roles of DSBs during IN-CA-independent viral transduction into macrophages.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Germany 1 2%
Canada 1 2%
Unknown 50 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 30%
Student > Master 9 17%
Researcher 7 13%
Student > Bachelor 6 11%
Student > Doctoral Student 2 4%
Other 7 13%
Unknown 6 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 34%
Medicine and Dentistry 10 19%
Biochemistry, Genetics and Molecular Biology 8 15%
Immunology and Microbiology 5 9%
Neuroscience 2 4%
Other 3 6%
Unknown 7 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2022.
All research outputs
#6,373,886
of 23,243,271 outputs
Outputs from Retrovirology
#324
of 1,111 outputs
Outputs of similar age
#52,134
of 194,145 outputs
Outputs of similar age from Retrovirology
#8
of 18 outputs
Altmetric has tracked 23,243,271 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,111 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,145 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.