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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis
|
|---|---|
| Published in |
BMC Systems Biology, February 2013
|
| DOI | 10.1186/1752-0509-7-16 |
| Pubmed ID | |
| Authors |
Kamil Erguler, Myrtani Pieri, Constantinos Deltas |
| Abstract |
The unfolded protein response (UPR) is a major signalling cascade acting in the quality control of protein folding in the endoplasmic reticulum (ER). The cascade is known to play an accessory role in a range of genetic and environmental disorders including neurodegenerative and cardiovascular diseases, diabetes and kidney diseases. The three major receptors of the ER stress involved with the UPR, i.e. IRE1 α, PERK and ATF6, signal through a complex web of pathways to convey an appropriate response. The emerging behaviour ranges from adaptive to maladaptive depending on the severity of unfolded protein accumulation in the ER; however, the decision mechanism for the switch and its timing have so far been poorly understood. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Cyprus | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| United States | 2 | 1% |
| Japan | 1 | <1% |
| Unknown | 132 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 34 | 25% |
| Student > Ph. D. Student | 26 | 19% |
| Student > Bachelor | 14 | 10% |
| Student > Master | 9 | 7% |
| Student > Doctoral Student | 7 | 5% |
| Other | 24 | 18% |
| Unknown | 23 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 28% |
| Biochemistry, Genetics and Molecular Biology | 27 | 20% |
| Medicine and Dentistry | 11 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 6% |
| Engineering | 7 | 5% |
| Other | 21 | 15% |
| Unknown | 25 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2013.
All research outputs
#14,638,545
of 23,881,329 outputs
Outputs from BMC Systems Biology
#516
of 1,126 outputs
Outputs of similar age
#111,021
of 195,303 outputs
Outputs of similar age from BMC Systems Biology
#8
of 19 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,126 research outputs from this source. They receive a mean Attention Score of 3.6. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,303 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.